The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 23, 2016
Filed:
Aug. 09, 2013
University of Tsukuba, Tsukuba-Shi, JP;
Center of Biotechnology of Sfax, University of Sfax, Mesrs, Sfax, TN;
Mitsutoshi Nakajima, Tsukuba, JP;
Marcos Neves, Tsukuba, JP;
Hiroko Isoda, Tsukuba, JP;
Ilyes Dammak, Sfax, TN;
Sami Sayadi, Sfax, TN;
University of Tsukuba, Tsukuba-shi, JP;
Center of Biotechnology of Sfax, University of Sfax, MESRS, Sfax, TN;
Abstract
The present invention relate to a highly efficient and novel method, using clean technologies, for obtaining a natural bioactive concentrate that is rich on polyphenols from olive mill water (OMW). The clean technologies integrate centrifugation, a drowning-out crystallization-based separation process, and vacuum evaporation. The method provides a highly-concentrated polyphenol isolate (up to 99% (mass fraction)) from other components presents in OMW, with up to half of the polyphenol content being hydroxytyrosol. The isolated polyphenols exhibit anti-oxidant, anti-microbial, anti-inflammatory, and anti-carcinogenic activities; they can be prepared as solid particles, as an aqueous solution, in an emulsion, or as lipidic-based nanoparticles. The isolated polyphenols can be used in the food industry, cosmetic industry, or pharmaceutical industry.