The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 09, 2016
Filed:
Dec. 28, 2011
Carolina Sousa Martin, Sevilla, ES;
Isabel Comino Montilla, Sevilla, ES;
Ana Real Calderon, Sevilla, ES;
Santiago Vivas Alegre, Sevilla, ES;
Angel Cebolla Ramirez, Sevilla, ES;
Carolina Sousa Martin, Sevilla, ES;
Isabel Comino Montilla, Sevilla, ES;
Ana Real Calderon, Sevilla, ES;
Santiago Vivas Alegre, Sevilla, ES;
Angel Cebolla Ramirez, Sevilla, ES;
Universidad De Sevilla, Sevilla, ES;
Abstract
The present invention, fitted in the medical-clinical sector, shows a method for monitoring the ingestion of gluten by measuring protein/gluten peptides present in fecal samples with antibodies against immunogenic peptides resistant to gastrointestinal digestion. The presence or absence of said immunogenic peptides is controlled by immunological assays based on reactive antibodies against immunogenic gluten peptides that are resistant to proteolysis. These assays may be quantitative techniques as ELISAs, or qualitative as rapid immunochromatographic assays, immunoblots, etc. These measures may also be applied to verify compliance with the gluten-free diet, to improve diagnosis in cases of refractory or severe symptoms of celiac disease, in cases in which a gluten-free diet is supposedly being respected, or to clinical research on the effectiveness of enzymatic therapies related with prolamin detoxification.