The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 07, 2016

Filed:

Jul. 30, 2013
Applicant:

Symrise Ag, Holzminden, DE;

Inventors:

Jens Michael Hilmer, Holzminden, DE;

Egon Gross, Holzminden, DE;

Gerhard Krammer, Holzminden, DE;

Jakob Peter Ley, Holzminden, DE;

Mechthild Gall, Greifswald, DE;

Uwe Bornscheuer, Griefswald, DE;

Maren Thomsen, Greifswald, DE;

Christin Peters, Greifswald, DE;

Patrick Jonczyk, Hannover, DE;

Sascha Beutel, Hannover, DE;

Thomas Scheper, Hannover, DE;

Assignee:

SYMRISE AG, Holzminden, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P 7/26 (2006.01); C12N 1/21 (2006.01); C12N 9/02 (2006.01); C12N 9/90 (2006.01); C12N 15/53 (2006.01); C12N 15/61 (2006.01); C12N 15/63 (2006.01); C12R 1/01 (2006.01); C12R 1/19 (2006.01); C12R 1/645 (2006.01); C12R 1/865 (2006.01); C12R 1/84 (2006.01);
U.S. Cl.
CPC ...
C12P 7/26 (2013.01); C12N 9/001 (2013.01); C12N 9/90 (2013.01); C12R 1/01 (2013.01); C12R 1/19 (2013.01); C12R 1/645 (2013.01); C12R 1/84 (2013.01); C12R 1/865 (2013.01); C12Y 103/01031 (2013.01); C12Y 505/01006 (2013.01); Y02P 20/52 (2015.11);
Abstract

A method for production of a dihydrochalcone, especially of phloretin, using a transgenic microorganism, containing a nucleic acid section (a), comprising or consisting of a gene coding for a bacterial chalcone isomerase, and/or a nucleic acid section (a'), comprising or consisting of a gene coding for a plant chalcone isomerase, and a nucleic acid section (b), comprising or consisting of a gene coding for a bacterial enoate reductase, corresponding transgenic microorganisms, containing a nucleic acid section (a), comprising or consisting of a gene coding for a bacterial chalcone isomerase, and/or a nucleic acid section (a′), comprising or consisting of a gene coding for a plant chalcone isomerase, and/or a nucleic acid section (b), comprising or consisting of a gene coding for a bacterial enoate reductase, and host cells, containing one or more identical or different such vectors.


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