The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 24, 2016

Filed:

Jul. 09, 2012
Applicants:

Xuan Wang, Tempe, AZ (US);

Elliot N. Miller, Indianapolis, IN (US);

Lorraine P. Yomano, Gainesville, FL (US);

Keelnatham T. Shanmugam, Gainesville, FL (US);

Lonnie O'neal Ingram, Gainesville, FL (US);

Inventors:

Xuan Wang, Tempe, AZ (US);

Elliot N. Miller, Indianapolis, IN (US);

Lorraine P. Yomano, Gainesville, FL (US);

Keelnatham T. Shanmugam, Gainesville, FL (US);

Lonnie O'Neal Ingram, Gainesville, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 13/00 (2006.01); C12P 7/56 (2006.01); C12P 7/46 (2006.01); C12P 7/10 (2006.01); C07K 14/245 (2006.01); C12N 9/02 (2006.01); C12P 7/06 (2006.01); C12P 7/16 (2006.01); C12P 7/18 (2006.01); C12P 7/40 (2006.01); C12P 7/44 (2006.01); C12P 7/54 (2006.01);
U.S. Cl.
CPC ...
C12P 13/001 (2013.01); C07K 14/245 (2013.01); C12N 9/0004 (2013.01); C12P 7/06 (2013.01); C12P 7/065 (2013.01); C12P 7/10 (2013.01); C12P 7/16 (2013.01); C12P 7/18 (2013.01); C12P 7/40 (2013.01); C12P 7/44 (2013.01); C12P 7/46 (2013.01); C12P 7/54 (2013.01); C12P 7/56 (2013.01); C12P 2203/00 (2013.01); Y02E 50/16 (2013.01); Y02E 50/17 (2013.01); Y02P 20/52 (2015.11);
Abstract

The subject invention pertains to overexpression of a putative oxidoreductase (ucpA) for increasing furfural tolerance in genetically modified microorganisms. Genetically modified microorganisms capable of overexpressing UcpA are also provided. Increased expression of ucpA was shown to increase furfural tolerance by 50%, and to permit the fermentation of sugars to products in the presence of 15 mM furfural.


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