The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2014

Filed:

Aug. 19, 2013
Applicant:

Codexis, Inc., Redwood City, CA (US);

Inventors:

Jack Liang, San Mateo, CA (US);

Stephane J. Jenne, Foster City, CA (US);

Emily Mundorff, Poughkeepsie, NY (US);

Charlene Ching, San Jose, CA (US);

John M. Gruber, Mountain View, CA (US);

Anke Krebber, Palo Alto, CA (US);

Gjalt W. Huisman, San Carlos, CA (US);

Assignee:

Codexis, Inc., Redwood City, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/02 (2006.01); C07K 14/00 (2006.01); C12N 9/04 (2006.01); C12P 7/22 (2006.01); C12Q 1/26 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0006 (2013.01); Y02E 50/17 (2013.01); C12P 7/22 (2013.01);
Abstract

The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.


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