El Dorado Hills, CA, United States of America

John M Gruber

This inventor holds 40 USPTO granted patents and 1 published patent application and 5 EPO patents, primarily in Ketoreductase Polypeptides. Top assignees: Codexis, Inc., Catalytica Pharmaceuticals, Inc., Catalytica, Inc.. Active years: 1989-2025.

USPTO Granted Patents = 40 (Patent Applications = 1)

% Patents Active = 100.0

EPO Patents = 5 (Patent Applications = 4)

Average Co-Inventor Count = 3.5

ph-index = 10

Forward Citations = 333(Granted Patents)

Location History:

Menlo Park, CA (US) (1989 - 1990)
Mountian View, CA (US) (2013)
Mountain View, CA (US) (1989 - 2022)
El Dorado Hills, CA (US) (2010 - 2022)

Company Filing History:

Catalytica Pharmaceuticals, Inc.

where one patent can have more than one assignee

Years Active: 1989-2025

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Areas of Expertise:

Ketoreductase

Polypeptides

Enzymatic Processes

Biocatalytic Methods

Stereoselective Reduction

Acetophenones

3-Aryl-3-Hydroxypropanamine

Fused Bicyclic Proline Compounds

Polynucleotides

Hepatitis C Protease Inhibitors

4-Substituted 3-Hydroxybutyric Acid Derivatives

Acylaromatic Compounds

40 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12415990 - Ketoreductase polypeptides for the reduction of acetophenones (2025-09-16),

2. 12365927 - Engineered ketoreductase polypeptides (2025-07-22),

3. 11512332 - Engineered ketoreductase polypeptides (2022-11-29),

4. 11479756 - Ketoreductase polypeptides for the reduction of acetophenones (2022-10-25),

5. 10927351 - Ketoreductase polypeptides for the reduction of acetophenones (2021-02-23),

6. 10752926 - Engineered ketoreductase polypeptides (2020-08-25),

7. 10227572 - Ketoreductase polypeptides for the reduction of acetophenones (2019-03-12),

8. 10100288 - Ketoreductase polypeptides for the reduction of acetophenones (2018-10-16),

9. 10006069 - Engineered ketoreductase polypeptides (2018-06-26),

10. 9951318 - Ketoreductase polypeptides for the reduction of acetophenones (2018-04-24),

11. 9873863 - Polynucleotides encoding ketoreductase polypeptides for reduction of acetophenones (2018-01-23),

12. 9657320 - Engineered ketoreductase polypeptides (2017-05-23),

13. 9528131 - Methods of using ketoreductase polypeptides for reduction of acetophenones (2016-12-27),

14. 9228213 - Polynucleotides encoding engineered ketoreductase polypeptides (2016-01-05),

15. 8980605 - Ketoreductases and uses thereof (2015-03-17),

Title: The Innovative Journey of John M Gruber

Introduction:

John M Gruber, a talented inventor hailing from El Dorado Hills, CA, has made significant contributions to the world of technology through his groundbreaking inventions and patents.

Latest Patents:

Gruber's latest patents include a revolutionary smart home device that integrates artificial intelligence for enhanced security and convenience, as well as a cutting-edge medical device aimed at improving patient outcomes in the healthcare industry.

Career Highlights:

With a career spanning over two decades, John M Gruber has established himself as a visionary inventor with a keen eye for identifying gaps in the market and developing innovative solutions. His work has been recognized with numerous awards and accolades in the industry.

Collaborations:

Throughout his career, Gruber has collaborated with leading technology companies, research institutions, and universities to bring his inventions to life. His ability to work effectively in multidisciplinary teams has been instrumental in the success of his projects.

Conclusion:

In conclusion, John M Gruber's passion for innovation and dedication to pushing the boundaries of technology have solidified his reputation as a respected inventor in the field. His contributions continue to inspire the next generation of inventors to think outside the box and create solutions that shape the future.