The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 19, 2011
Filed:
Aug. 08, 2007
Catherine Tachdjian, San Diego, CA (US);
Xiao-qing Tang, San Diego, CA (US);
Sara Werner, San Diego, CA (US);
Marketa Rinnova, Urbana, IL (US);
Qing Chen, San Diego, CA (US);
Guy Servant, San Diego, CA (US);
Xiaodong LI, San Diego, CA (US);
Feng Zhang, San Diego, CA (US);
Haitian Liu, San Diego, CA (US);
Albert Zlotnik, San Diego, CA (US);
Mark Zoller, La Jolla, CA (US);
Boris Klebansky, Demarest, NJ (US);
Richard Fine, Ridgewood, NJ (US);
Xinshan Kang, Pine Brook, NJ (US);
Catherine Tachdjian, San Diego, CA (US);
Xiao-Qing Tang, San Diego, CA (US);
Sara Werner, San Diego, CA (US);
Marketa Rinnova, Urbana, IL (US);
Qing Chen, San Diego, CA (US);
Guy Servant, San Diego, CA (US);
Xiaodong Li, San Diego, CA (US);
Feng Zhang, San Diego, CA (US);
Haitian Liu, San Diego, CA (US);
Albert Zlotnik, San Diego, CA (US);
Mark Zoller, La Jolla, CA (US);
Boris Klebansky, Demarest, NJ (US);
Richard Fine, Ridgewood, NJ (US);
Xinshan Kang, Pine Brook, NJ (US);
Senomyx, Inc., San Diego, CA (US);
Abstract
The present invention provides compounds including substituted thienopyrimidinone derivatives of Formula (IIc) as ligands for modulating chemosensory receptors: These compounds are useful as sweet taste enhancers in comestible or medicinal compositions. The present invention also provides screening methods for identifying modifiers of chemosensory receptors and their ligands, e.g., by determining whether a test entity is suitable to interact with one or more interacting sites within the Venus flytrap domains of the chemosensory receptors as well as modifiers capable of modulating chemosensory receptors and their ligands.