The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 08, 2008

Filed:

Mar. 25, 2003
Applicants:

Márcio Luis Andrade Silva, Franca, BR;

Sérgio Albuquerque, Ribeirão Preto, BR;

Gustavo Henrique Bianco Souza, Pedregulho, BR;

Jairo Kenupp Bastos, Rebeirão Preto, BR;

Rosângela Silva, Jaboticabal, BR;

Inventors:

Márcio Luis Andrade Silva, Franca, BR;

Sérgio Albuquerque, Ribeirão Preto, BR;

Gustavo Henrique Bianco Souza, Pedregulho, BR;

Jairo Kenupp Bastos, Rebeirão Preto, BR;

Rosângela Silva, Jaboticabal, BR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 305/12 (2006.01); C07D 307/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention refers to a process to obtain lignans, especially to obtain cubebin and methylpluviatolide from leaves ofor. It also refers to a process to obtain semi-synthetic derivatives of cubebin, especially dibenzylbutirloactonic lignans, such as: hinokinin, o-acetyl cubebin, o-methyl cubebin, 6,6'-dinitrohinokinine and o-dimethylethylamine cubebin and other derivatives which may be obtained, as well as to obtain methylpluviatolide derivatives, which are used to manufacture drugs to provide activity at least five times higher than observed for gentian violet and other compounds used heretofore for blood treatment and Chagas' disease prophylaxis.


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