Company Filing History:
Years Active: 2008-2009
Title: Rosângela Silva: Innovator in Lignan Derivatives
Introduction
Rosângela Silva is a notable inventor based in Jaboticabal, Brazil. He has made significant contributions to the field of chemistry, particularly in the development of processes for obtaining lignans and their derivatives. His work has implications for drug manufacturing, especially in the treatment of Chagas' disease.
Latest Patents
Rosângela Silva holds a patent for a process to obtain dibenzylbutyrolactonic lignans and synthetic derivatives from lignans that exhibit anti-Chagas chemoprophylactic and therapeutic activities. This invention focuses on the extraction of cubebin and methylpluviatolide from specific plant leaves. Additionally, it details the creation of semi-synthetic derivatives of cubebin, including hinokinin, o-acetyl cubebin, o-methyl cubebin, 6,6'-dinitrohinokinine, and o-dimethylethylamine cubebin. These derivatives are designed to enhance the efficacy of drugs, providing activity at least five times greater than that of gentian violet and other previously used compounds for blood treatment and Chagas' disease prophylaxis.
Career Highlights
Rosângela Silva is affiliated with the Fundação de Amparo à Pesquisa do Estado de São Paulo, where he continues to advance his research in lignan derivatives. His innovative work has positioned him as a key figure in the field of medicinal chemistry.
Collaborations
He has collaborated with notable colleagues, including Márcio Luis Andrade Silva and Sérgio Albuquerque, contributing to the advancement of research in his area of expertise.
Conclusion
Rosângela Silva's contributions to the field of lignan derivatives highlight his innovative spirit and dedication to improving therapeutic options for diseases like Chagas. His work exemplifies the importance of research and innovation in the medical field.