Sérgio Albuquerque

Title: Innovations by Inventor Sérgio Albuquerque

Introduction

Sérgio Albuquerque is a notable inventor based in Ribeirão Preto, Brazil. He has made significant contributions to the field of chemistry, particularly in the development of processes related to lignans. His work focuses on creating compounds that have therapeutic applications, especially in the treatment and prevention of Chagas disease.

Latest Patents

Sérgio Albuquerque holds a patent for a process to obtain dibenzylbutyrolactonic lignans and synthetic derivatives from lignans that exhibit anti-Chagas chemoprophylactic and therapeutic activities. This invention specifically details a method for extracting lignans, such as cubebin and methylpluviatolide, from plant leaves. Additionally, it outlines the creation of semi-synthetic derivatives of cubebin, including hinokinin, o-acetyl cubebin, o-methyl cubebin, 6,6'-dinitrohinokinine, and o-dimethylethylamine cubebin. These derivatives are crucial for developing drugs that demonstrate activity significantly higher than traditional treatments for blood disorders and Chagas disease.

Career Highlights

Sérgio Albuquerque is affiliated with the Fundação de Amparo à Pesquisa do Estado de São Paulo, where he continues to advance his research and innovations. His work has garnered attention for its potential impact on public health, particularly in regions affected by Chagas disease.

Collaborations

Throughout his career, Sérgio has collaborated with notable colleagues, including Márcio Luis Andrade Silva and Gustavo Henrique Bianco Souza. These partnerships have enhanced the scope and effectiveness of his research endeavors.

Conclusion

Sérgio Albuquerque's innovative work in the field of lignans represents a significant advancement in therapeutic applications for Chagas disease. His contributions not only highlight the importance of research in public health but also demonstrate the potential of natural compounds in developing effective treatments.