Company Filing History:
Years Active: 2008-2009
Title: Márcio Luis Andrade Silva: Innovator in Lignan Derivatives
Introduction
Márcio Luis Andrade Silva is a notable inventor based in Franca, Brazil. He has made significant contributions to the field of chemistry, particularly in the development of processes related to lignans. His innovative work has led to the creation of a patent that addresses important therapeutic applications.
Latest Patents
Márcio holds a patent for a process to obtain dibenzylbutyrolactonic lignans and synthetic derivatives from lignans that exhibit anti-Chagas chemoprophylactic and therapeutic activities. This invention focuses on the extraction of lignans, specifically cubebin and methylpluviatolide, from plant leaves. The patent also details the production of semi-synthetic derivatives of cubebin, including hinokinin, o-acetyl cubebin, o-methyl cubebin, 6,6'-dinitrohinokinine, and o-dimethylethylamine cubebin. These derivatives are crucial for developing drugs that demonstrate activity significantly higher than traditional treatments for blood disorders and Chagas' disease prophylaxis.
Career Highlights
Márcio is affiliated with the Fundação de Amparo à Pesquisa do Estado de São Paulo, where he continues to advance his research in the field of lignans. His work has garnered attention for its potential impact on drug development and therapeutic applications.
Collaborations
He has collaborated with notable colleagues, including Sérgio Albuquerque and Gustavo Henrique Bianco Souza, contributing to a dynamic research environment that fosters innovation.
Conclusion
Márcio Luis Andrade Silva's contributions to the field of lignan derivatives highlight his role as an important inventor in Brazil. His patented processes not only advance scientific knowledge but also hold promise for significant therapeutic applications.