The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 22, 2025

Filed:

Dec. 08, 2016
Applicant:

Basf SE, Ludwigshafen am Rhein, DE;

Inventors:

Katrin Treier-Marxen, Ludwigshafen, DE;

Petra Deckert, Bammental, DE;

Andreas Schaedler, Weyher, DE;

Vaidotas Navickas, Mannheim, DE;

Volker Wengert, Worms, DE;

Thomas Kaeding, Mannheim, DE;

Assignee:

BASF SE, Ludwigshafen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 1/02 (2006.01); B01D 61/14 (2006.01); B01D 61/16 (2006.01); C07K 1/14 (2006.01); C07K 1/30 (2006.01); C12P 21/02 (2006.01);
U.S. Cl.
CPC ...
C12N 1/02 (2013.01); B01D 61/147 (2013.01); B01D 61/16 (2013.01); C07K 1/145 (2013.01); C07K 1/30 (2013.01); C12P 21/02 (2013.01); B01D 2311/04 (2013.01); B01D 2311/18 (2013.01); B01D 2315/16 (2013.01);
Abstract

The present invention is directed to a method of purifying a protein of interest from the particulate matter of a fermentation broth comprising the step of purifying the protein of interest from the particulate matter of the fermentation broth, wherein the step of purifying the protein of interest from the particulate matter of the fermentation broth comprises one or more washing steps, which comprises contacting the particulate matter with a washing solution comprising one or more conditions that favor the solubilization of the protein of interest and/or the desorption of the protein of interest from the particulate matter.


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