Title: Zuzana Jouklova - Innovator in Hyaluronan Derivatives
Introduction
Zuzana Jouklova is a notable inventor based in Litomysl, Czech Republic. She has made significant contributions to the field of hyaluronan derivatives, particularly through her innovative patent applications. Although she currently holds no granted patents, her work demonstrates a commitment to advancing scientific knowledge and applications.
Latest Patent Applications
Zuzana Jouklova's latest patent application is titled "Crosslinked Hyaluronan Derivative, Method of Preparation Thereof, Hydrogel and Microfibers Based Thereon." This invention relates to a crosslinked hyaluronan derivative in the form of a hydrogel or microfibers. The method of preparation involves a C—C coupling reaction, which is performed via the reaction of a hyaluronan derivative carrying a terminal aryl-halide and/or aryl-borate group, and a hyaluronan derivative carrying an alkenyl or alkynyl group. This reaction takes place in water, phosphate buffer, or a mixture of an organic acid and an alcohol, and in the presence of a palladium active catalyst. The palladium active catalyst may include a complex of palladium (II) acetate and an inorganic or organic base, or a complex of palladium (II) and 2-amino-4,6-dihydroxypyrimidine.
Conclusion
Zuzana Jouklova is an innovative inventor whose work in hyaluronan derivatives showcases her dedication to scientific advancement. Her latest patent application reflects her expertise and potential impact in the field.