Company Filing History:
Years Active: 2001-2002
Title: Zsolt Holló: Innovator in Multi-Drug Resistance Evaluation
Introduction
Zsolt Holló is a prominent inventor based in Budapest, Hungary. He has made significant contributions to the field of biotechnology, particularly in the evaluation of multi-drug resistance in cells. With a total of 2 patents, his work has implications for clinical screening and drug development.
Latest Patents
Holló's latest patents focus on assay and reagent kits designed for the quantitative in vitro determination of multi-drug resistance in cells. These patents disclose methods and reagent kits that allow for the clinical screening of potential modulators of multi-drug resistant transport activity. The innovative method involves measuring the accumulation rate of free calcein within cells after exposure to a cell-permeable form of calcein, which is a substrate for MDR proteins. This approach enables rapid screening of inhibitors and evaluation of the functional type of multi-drug resistance exhibited by the cells.
Career Highlights
Zsolt Holló is currently associated with Solvo Biotechnology, a company known for its advancements in drug delivery and transport research. His work at Solvo has positioned him as a key figure in the biotechnology sector, contributing to the understanding of drug resistance mechanisms.
Collaborations
Holló has collaborated with notable colleagues, including László Homolya and Balázs Sarkadi. These collaborations have further enhanced the research and development efforts in the field of multi-drug resistance.
Conclusion
Zsolt Holló's innovative work in the evaluation of multi-drug resistance showcases his commitment to advancing biotechnology. His patents and collaborations reflect a dedication to improving clinical outcomes in drug resistance management.