Company Filing History:
Years Active: 1980
Title: Zofia Plociennik: Innovator in Pharmaceutical Chemistry
Introduction
Zofia Plociennik is a notable inventor based in Warsaw, Poland. She has made significant contributions to the field of pharmaceutical chemistry, particularly through her innovative work on polyene macrolides. Her research has led to the development of compounds that exhibit high pharmacological activity against various fungal infections.
Latest Patents
Zofia Plociennik holds a patent for "Salts of N-glycosyl derivatives of polyene macrolides." This patent describes new compounds, specifically N-methylglucamine salts of N-glycosyl derivatives of polyene macrolides, including amphotericin B, polifungin, and nystatin. These compounds are prepared by reacting an amino group containing polyene macrolide with an aldose or ketose mono- or oligosaccharide in an organic solvent medium. The resulting N-glycosyl derivatives are precipitated from the reaction medium and transformed into N-methylglucamine salts, which are then crystallized from higher alkanols.
Career Highlights
Throughout her career, Zofia has worked with esteemed institutions such as Politechnika Gdańska and the Pharmaceutical Industry Institute. Her work has been instrumental in advancing the understanding and application of polyene macrolides in treating fungal infections.
Collaborations
Zofia has collaborated with notable colleagues, including Leonard S. Falkowski and Zuzanna Kowszyk-Gindifer. These partnerships have contributed to her research and the successful development of her patented compounds.
Conclusion
Zofia Plociennik's contributions to pharmaceutical chemistry and her innovative patents highlight her role as a significant figure in the field. Her work continues to impact the treatment of fungal infections, showcasing the importance of innovation in healthcare.