Company Filing History:
2 out of 7 
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1 out of 17 Years Active: 2013-2017
Title: Zicai Liang: Innovator in Nucleotide and RNA Technologies
Introduction
Zicai Liang is a prominent inventor based in Beijing, China. He has made significant contributions to the fields of nucleotide and oligonucleotide synthesis, as well as RNA technology. With a total of 4 patents, his work has implications for both therapeutic applications and biotechnological advancements.
Latest Patents
Liang's latest patents include innovative processes for synthesizing nucleotides and oligonucleotides. One notable patent describes a liquid phase synthesis process that allows for the preparation of nucleotides and/or oligonucleotides. This process involves protecting the 2'-hydroxyl group with a sterically hindered silane structure, enabling the direct protection of the 3' phosphate group(s) with β-cyanoethyl groups. This method facilitates large-scale preparation of oligonucleotides without the limitations of solid carriers or synthesizers. Another significant patent focuses on the preparation and application of double-stranded RNA molecules that are stable in mammalian body fluids. These RNA molecules, composed solely of unmodified nucleotides, have potential applications in immunotherapy and siRNA drug development.
Career Highlights
Throughout his career, Zicai Liang has worked with notable companies in the biotechnology sector, including Biomics Biotechnologies, Co., Ltd. and Suzhou Ribo Life Science Co., Ltd. His expertise in nucleotide chemistry and RNA technology has positioned him as a key figure in the development of innovative biotechnological solutions.
Collaborations
Liang has collaborated with several professionals in his field, including Zhen Xi and Jinyu Huang. These collaborations have contributed to the advancement of his research and the successful development of his patented technologies.
Conclusion
Zicai Liang's contributions to nucleotide and RNA technologies highlight his role as an influential inventor in the biotechnology industry. His innovative patents and collaborations continue to pave the way for advancements in therapeutic applications and biotechnological processes.