Title: Ziad S Kawar: Innovator in Antibody Research
Introduction
Ziad S Kawar is an accomplished inventor based in Oklahoma City, OK (US). He has made significant contributions to the field of antibody research, particularly in the development of anti-P-selectin antibodies. Although he currently holds no granted patents, his work has the potential to impact various medical applications.
Latest Patent Applications
Ziad's latest patent applications include "Anti-P Selectin Antibodies and Methods of Their Use and Identification." This application discloses antibodies that specifically bind to P-selectin and block the binding of PSGL-1 to P-selectin. These anti-P-selectin antibodies may also cause the dissociation of preformed P-selectin/PSGL-1 complexes. The disclosure identifies a previously unrecognized, near N-terminal antibody binding domain of P-selectin, which is crucial for the function-blocking antibodies. These antibodies may be chimeric, human, or humanized and have dual functions in both blocking the binding of PSGL-1 to P-selectin and causing the dissociation of preformed complexes. Such antibodies and their binding fragments may be utilized in treating various inflammatory and thrombotic disorders. Screening methods for identifying these antibodies are also included in the application.
Conclusion
Ziad S Kawar is a notable figure in the field of antibody research, with promising applications that could lead to advancements in medical treatments. His innovative work continues to pave the way for future developments in the treatment of inflammatory and thrombotic conditions.