Zhuo-Hua Pan

This inventor holds 12 USPTO granted patents and 12 published patent applications, plus 2 CIPO patents and 3 EPO patents. Top assignees: Wayne State University, Salus University. Active years: 2013-2025.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Zhuo-Hua Pan. Retrieved from https://idiyas.com/inventor/zhuo-hua-pan

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

USPTO Granted Patents = 12 (Patent Applications = 12)

% Patents Active = 100.0

CIPO Patents = 2 (Patent Applications = 5)

EPO Patents = 3 (Patent Applications = 7)

Average Co-Inventor Count = 1.5

ph-index = 2

Forward Citations = 35(Granted Patents)

Company Filing History:

12 out of 603

Wayne State University

where one patent can have more than one assignee

Years Active: 2013-2025

Loading Chart...

12 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12343408 - AAV-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells (2025-07-01),

2. 12234267 - Identification of mutations in channelopsin variants having improved light sensitivity and methods of use thereof (2025-02-25),

3. 11883463 - Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids (2024-01-30),

4. 11583595 - Modified mGluR6 promoter and methods of use (2023-02-21),

5. 11041004 - Identification of mutations in channelopsin variants having improved light sensitivity and methods of use thereof (2021-06-22),

6. 10947281 - Identification of channelrhodopsin-2 (ChR2) mutations and methods of use (2021-03-16),

7. 10307492 - Modified MGLUR6 promoter and methods of use (2019-06-04),

8. 9968689 - AAV-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells (2018-05-15),

9. 9730981 - Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids (2017-08-15),

10. 9730888 - Method of enhancing delivery of therapeutic compounds to the eye (2017-08-15),

11. 9453241 - AAV-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells (2016-09-27),

12. 8470790 - Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids (2013-06-25),

Title: Zhuo-Hua Pan: Innovator in Vision Restoration

Introduction

Zhuo-Hua Pan, based in Troy, MI, is a prominent inventor known for his significant contributions to the field of vision restoration. With an impressive portfolio of 12 patents, Pan has dedicated his research to developing innovative solutions aimed at improving or restoring vision in patients with retinal diseases.

Latest Patents

Among his latest patents is the invention titled "AAV-mediated subcellular targeting of heterologous rhodopsins in retinal ganglion cells." This groundbreaking work focuses on the use of recombinant AAV vectors to selectively express microbial type rhodopsins, such as channelrhodopsin-2 and halorhodopsin, in retinal ganglion cells. By employing specific sorting motifs in the vectors, Pan’s method allows precise targeting of transgene expression, significantly enhancing the potential for restoring visual perception in those affected by retinal conditions.

Another notable patent involves the "Identification of mutations in channelopsin variants having improved light sensitivity." This invention provides compositions and kits featuring mutant CoChop proteins, designed to preserve or restore phototransduction in subjects with impaired vision. The methods derived from this research hold promise for bringing vision restoration to normal levels, particularly for individuals suffering from visual impairments.

Career Highlights

Zhuo-Hua Pan has held significant positions in reputable institutions, including Wayne State University and Salus University. His work is recognized for its innovative approach to tackling complex issues related to vision and retinal health.

Collaborations

Throughout his career, Pan has collaborated with esteemed colleagues, including Alexander M Dizhoor and Qi Lu. These partnerships have played a pivotal role in advancing research initiatives and pushing the boundaries of knowledge in the field of vision restoration.

Conclusion

Zhuo-Hua Pan continues to be a leading figure in the innovation landscape surrounding retinal research. His inventions not only demonstrate technical ingenuity but also reflect a deep commitment to improving the quality of life for individuals affected by vision loss. As he pushes forward in his research, the potential for his innovations to redefine the possibilities of vision restoration remains promising.

Profile summary based on public USPTO records.