Location History:
- Cheshire, CO (US) (2016)
- Wallingford, CT (US) (2018 - 2019)
- Cheshire, CT (US) (2002 - 2023)
Company Filing History:
10 out of 3,685 
3 out of 42 Years Active: 2002-2023
Title: **Zhizhen Barbara Zheng: Innovator in Kinase Inhibition and HIV Research**
Introduction
Zhizhen Barbara Zheng, a prominent inventor based in Cheshire, CT, is recognized for her significant contributions to the field of medicinal chemistry. With a remarkable portfolio of 13 patents, she has focused her research on developing innovative compounds that have potential therapeutic applications. Her work emphasizes the need for advanced treatments for conditions such as necrosis, inflammation, and HIV.
Latest Patents
Among Zheng's latest innovations are two key patents that showcase her expertise:
1. **Aminopyrrolotriazines as Kinase Inhibitors** - This patent discloses compounds useful as kinase modulators, specifically targeting RIPK 1 modulation. The methods outlined for using these compounds highlight their potential in treating diseases related to necrosis and inflammation, among other indications.
2. **Pyridin-3-yl Acetic Acid Derivatives as Inhibitors of Human Immunodeficiency Virus Replication** - This patent details compounds capable of inhibiting HIV integrase. The disclosure includes pharmaceutically acceptable salts and compositions, further expanding its use in treating individuals infected with HIV or AIDS.
Career Highlights
Zhizhen Barbara Zheng has made notable strides in her career while working with prestigious organizations such as Bristol-Myers Squibb Company and Viiv Healthcare UK (No.5) Limited. Her work at these companies has enabled her to develop critical innovations that contribute meaningfully to modern medicine.
Collaborations
Throughout her career, Zheng has collaborated with esteemed colleagues including Stanley V. D'Andrea and B. Narasimhulu Naidu. These partnerships have fostered a rich environment for innovation and discovery, leading to breakthroughs in the pharmaceutical sciences.
Conclusion
Zhizhen Barbara Zheng is an influential figure in the field of medicinal chemistry, with her 13 patents serving as a testament to her commitment to innovation. Through her extensive work on kinase inhibitors and HIV-related treatments, she continues to make strides that have the potential to transform patient care and advance medical research. Her dedication to her craft and her collaborations with industry leaders underscore her vital role in the ongoing quest for effective therapies.