Company Filing History:
1 out of 179 
1 out of 1 Years Active: 2022
Title: Zhehuan Chen: Innovator in Cancer Research
Introduction
Zhehuan Chen is a notable inventor based in Jersey City, NJ (US). He has made significant contributions to the field of cancer research, particularly in the development of innovative technologies for studying multiple myeloma. His work focuses on creating dynamic environments that mimic the human body, allowing for more effective evaluation of cancer treatments.
Latest Patents
Zhehuan Chen holds a patent for a "Pumpless platform for high-throughput dynamic multicellular culture and chemosensitivity evaluation." This invention provides an ex vivo dynamic multiple myeloma cancer niche contained in a pumpless perfusion culture device. The dynamic multiple myeloma cancer niche includes a three-dimensional tissue construct containing a dynamic ex vivo bone marrow niche, which contains a mineralized bone-like tissue with viable osteoblasts. These osteoblasts are self-organized into cohesive multiple cell layers, supported by an extracellular matrix secreted by the viable adherent osteoblasts. The microenvironment is dynamically perfused by nutrients and dissolved gas molecules, allowing for optimal conditions for human myeloma cells seeded from a biospecimen composition. The human myeloma cells are in contact with osteoblasts of the bone marrow niche, and their viability is maintained by this innovative cancer niche.
Career Highlights
Throughout his career, Zhehuan Chen has worked with esteemed institutions such as Stevens Institute of Technology and Hackensack Meridian Health Center for Discovery and Innovation. His research has focused on enhancing the understanding of cancer biology and improving therapeutic strategies.
Collaborations
Zhehuan Chen has collaborated with notable colleagues, including Woo Young Lee and Jenny Zilberberg. These partnerships have contributed to the advancement of his research and the development of innovative solutions in cancer treatment.
Conclusion
Zhehuan Chen's work exemplifies the intersection of innovation and cancer research. His patented technologies are paving the way for more effective cancer therapies and improving the understanding of complex cancer environments. His contributions are vital to the ongoing fight against multiple myeloma and other cancers.