Zhaogang Yang

Title: Innovations by Inventor Zhaogang Yang in Therapeutic Exosomes

Introduction

Zhaogang Yang, an accomplished inventor based in Columbus, OH, has made significant contributions to the field of therapeutic exosomes. With two patents to his name, Yang's work focuses on advanced biotechnology and cell transfection techniques that hold promise for medical applications.

Latest Patents

Yang's latest patent is a groundbreaking method for producing therapeutic extracellular vesicles (EVs) from nanoelectroporation and other non-endocytic cell transfection. This innovative process involves laying donor cells on a specially designed chip surface, where various plasmids and transfection vectors are added to a buffer. By applying a pulsulatic electric field across the cells and the plasmids buffer solution, Yang enables the efficient collection of high copies of functional nucleic acids and biomolecules secreted by the transfected cells. The patented chip features a three-dimensional (3D) nanochannel electroporation biochip, which is specifically engineered to handle large quantities of donor cells, thus enhancing the production capacity of therapeutic EVs.

Career Highlights

As a member of the Ohio State Innovation Foundation, Yang has been instrumental in driving research and development in biotechnological innovations. His expertise and dedication have facilitated advancements in the production and application of therapeutic EVs, which could significantly impact various fields including regenerative medicine and gene therapy.

Collaborations

Throughout his career, Zhaogang Yang has worked alongside notable colleagues, including Ly James Lee and Junfeng Shi. This collaborative spirit fosters an environment of creativity and innovation, further enhancing the potential of their research achievements in the biotechnology sector.

Conclusion

Zhaogang Yang's inventive approach to producing therapeutic exosomes showcases the transformative power of innovation in biotechnology. His patents reflect not only his technical expertise but also his commitment to advancing medical technologies that can potentially lead to significant breakthroughs in treatment methods. With his continued contributions, Yang is poised to make lasting impacts in the field of therapeutic applications.