Zengpeng Han

Title: Zengpeng Han: Innovator in Recombinant Adeno-Associated Virus Preparation

Introduction

Zengpeng Han is a notable inventor based in Wuhan, China. He has made significant contributions to the field of biotechnology, particularly in the preparation of recombinant adeno-associated viruses (rAAV). His innovative methods have the potential to advance gene therapy and related applications.

Latest Patents

Zengpeng Han holds a patent for a method, system, and recombinant bacmid for the preparation of recombinant adeno-associated virus. This patent outlines a comprehensive approach that includes preparing a shuttle plasmid and a corresponding recombinant bacmid. The shuttle plasmid contains an rAAV gene of interest flanked by inverted terminal repeats, integrated with a heterologous functional gene fragment. The recombinant bacmid includes an expression cassette of functional protein components necessary for the assembly of the rAAV. The process involves integrating the rAAV ITR-GOI and the expression cassette using the shuttle plasmid and recombinant bacmid, ultimately transfecting a host cell line with the recombinant bacmid.

Career Highlights

Zengpeng Han is affiliated with the Chinese Academy of Sciences, where he conducts his research and development activities. His work has garnered attention for its innovative approach to gene therapy, showcasing his expertise in molecular biology and virology.

Collaborations

Zengpeng has collaborated with notable colleagues such as Yang Wu and Fuqiang Xu. Their combined efforts contribute to the advancement of research in the field of recombinant viruses.

Conclusion

Zengpeng Han's contributions to the preparation of recombinant adeno-associated viruses highlight his role as a leading inventor in biotechnology. His innovative methods and collaborations continue to pave the way for advancements in gene therapy and related fields.