Location History:
- Suffern, NY (US) (2008)
- San Diego, CA (US) (2010 - 2011)
Company Filing History:
2 out of 242 
1 out of 54 
1 out of 88 
Years Active: 2008-2025
Title: Ze'ev Ronai: Innovator in Cancer Treatment
Introduction
Ze'ev Ronai is a prominent inventor based in San Diego, California, known for his significant contributions to cancer research and treatment. With a total of four patents to his name, Ronai has focused on innovative methods that leverage the gut microbiota and transcription factors to combat cancer.
Latest Patents
Ronai's latest patents include groundbreaking work on the gut microbiota and its role in cancer treatment. One of his notable inventions discusses how the ubiquitin ligase, RNF5, regulates gut microbiota composition and influences the immune checkpoint response to tumors. His research indicates that RNF5 deficient animals show significant inhibition of tumor development alongside an altered gut microbiota composition. Additionally, he has disclosed methods for treating cancer by administering selected bacterial species and/or prebiotics that promote the growth of these species, either alone or in combination with anti-cancer agents. Another significant patent focuses on inhibiting ATF2 activity to treat cancer, particularly in tumor cells resistant to conventional therapies. This invention provides methods for identifying strategies to inhibit a transcription factor that contributes to cell resistance and apoptosis inhibition, utilizing an inhibitory ATF2 N-terminal fragment.
Career Highlights
Throughout his career, Ze'ev Ronai has worked with esteemed institutions such as Mount Sinai School of Medicine and the Burnham Institute for Medical Research. His research has been pivotal in advancing our understanding of cancer biology and treatment methodologies.
Collaborations
Ronai has collaborated with notable colleagues, including Anindita Bhoumik and Nicholas D. P. Cosford, contributing to a rich exchange of ideas and research in the field of cancer treatment.
Conclusion
Ze'ev Ronai's innovative work in cancer treatment exemplifies the potential of combining microbiota research with traditional therapeutic approaches. His patents reflect a commitment to advancing medical science and improving patient outcomes in the fight against cancer.