This inventor holds 2 USPTO granted patents. Top assignees: Spofa United Pharmaceutical Works, Spofa, Spojene Podniky Pro Zdravotnickou Vyrobu. Active years: 1979-1986.
Company Filing History:
1 out of 8 
1 out of 16 Years Active: 1979-1986
Title: Zdenek Roubal: Innovator in Pharmaceutical Chemistry
Introduction
Zdenek Roubal is a notable inventor based in Prague, Czech Republic. He has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of compounds with therapeutic applications. His work has led to the issuance of multiple patents, showcasing his innovative approach to drug development.
Latest Patents
Roubal holds 2 patents, with his latest inventions focusing on compounds that exhibit strong analgesic and anti-inflammatory properties. One of his notable patents is for the compound 3-(2-(2-benzimidazolyl) benzolyloxyethyl)-4(3H)-quinazolinone. This compound demonstrates strong analgesic activity with minimal toxicity in laboratory mice. The preparation process involves acylation of 3-(2-hydroxyethyl)-4(3H)-quinazolinone with a reactive derivative of 2-(2-benzimidazolyl)benzoic acid. Another significant invention is a technique for preparing a novel anti-inflammatory agent comprising 2-phenyl-2-carboxyethyl 1-(p-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetate, which is synthesized by reacting indomethacin with tropic acid.
Career Highlights
Throughout his career, Zdenek Roubal has worked with several prominent companies in the pharmaceutical industry. He has been associated with Spofa, a well-known pharmaceutical manufacturer, as well as Spojene Podniky Pro Zdravotnickou Vyrobu and Spofa United Pharmaceutical Works. His experience in these organizations has contributed to his expertise in drug formulation and development.
Collaborations
Roubal has collaborated with notable colleagues in his field, including Ludmila Fisnerova and Jaroslava Grimova. These partnerships have facilitated the exchange of ideas and advancements in pharmaceutical research.
Conclusion
Zdenek Roubal's contributions to pharmaceutical chemistry through his innovative patents and collaborations highlight his role as a significant inventor in the industry. His work continues to impact the development of effective therapeutic agents.