Zbigniew D Darzynkiewicz

Title: Zbigniew D. Darzynkiewicz: Innovator in DNA Detection Methods

Introduction

Zbigniew D. Darzynkiewicz is a notable inventor based in Chappaqua, NY (US). He has made significant contributions to the field of molecular biology, particularly in the detection of halogenated precursors incorporated into DNA. His innovative methods have implications for various applications, including cell proliferation analysis and genotoxicity tests.

Latest Patents

Zbigniew D. Darzynkiewicz holds a patent for a method titled "Detection of halogenated precursors incorporated into DNA." This method utilizes selective photolysis of DNA by ultraviolet (UV) light at the sites of incorporated halogenated precursors, such as thymidine base analogs. The technique allows for the marking of DNA single strand breaks with fluorescent labels, enabling analysis through flow cytometry or fluorescence microscopy. This method is versatile and can be applied to cells in suspension, thin tissue sections, bacteria, and viruses.

Career Highlights

Zbigniew D. Darzynkiewicz is affiliated with New York Medical College, where he has contributed to advancing research in molecular biology. His work has been instrumental in developing techniques that enhance the understanding of DNA interactions and cellular processes.

Collaborations

Throughout his career, Zbigniew has collaborated with esteemed colleagues, including Xun Li and Frank N. Traganos. These collaborations have further enriched his research and contributed to the scientific community's knowledge in the field.

Conclusion

Zbigniew D. Darzynkiewicz is a prominent figure in the realm of DNA detection methods, with a patent that showcases his innovative approach to molecular biology. His contributions continue to influence research and applications in the field.