Zaohua Huang

Title: Zaohua Huang: Innovator in HIV Research

Introduction

Zaohua Huang is a prominent inventor based in Palmetto Bay, Florida. He has made significant contributions to the field of HIV research, particularly through his innovative approaches utilizing CRISPR technology. His work focuses on developing methods to effectively treat latent HIV infections.

Latest Patents

Zaohua Huang holds a patent for "Methods for screening and using CRISPR/Cas9 guidance RNA sequence from HIV provirus genome." This invention pertains to compositions and methods for identifying gRNAs that are effective in treating a latent HIV infection. An embodiment of the invention provides a cell that incorporates a gene expressing a CRISPR-Cas protein and an HIV pseudovirus genome. The HIV pseudovirus genome includes a first marker gene encoding a first marker protein under the control of the HIV-1 LTR promoter and a second marker gene inserted into the nef gene of the HIV pseudovirus, encoding a second marker protein under the control of a constitutive promoter. The patent also describes screening methods for identifying gRNAs that can treat latent HIV infections, as well as compositions comprising a CRISPR-Cas protein and gRNAs for treatment.

Career Highlights

Zaohua Huang is affiliated with Florida International University, where he conducts research and collaborates with other experts in the field. His work has garnered attention for its potential to revolutionize HIV treatment strategies.

Collaborations

One of his notable collaborators is Madhavan Nair, with whom he has worked on various research projects related to HIV and CRISPR technology.

Conclusion

Zaohua Huang's innovative work in HIV research exemplifies the potential of CRISPR technology in addressing complex medical challenges. His contributions are paving the way for new treatment options for those affected by latent HIV infections.