This inventor holds 1 USPTO granted patent. Top assignee: Jiangnan University. Active years: 2019.
Company Filing History:
Years Active: 2019
Title: Zaiwei Man: Innovator in Amino Acid Production
Introduction
Zaiwei Man is a notable inventor based in Wuxi, China. He has made significant contributions to the field of amino acid production through his innovative research and development efforts. His work focuses on enhancing the yield of L-arginine, a vital amino acid, using advanced microbial fermentation techniques.
Latest Patents
Zaiwei Man holds a patent titled "Method for increasing yield of L-arginine by knocking out Flavin reductases." This invention discloses a method that involves knocking out flavin reductases to increase the yield of L-arginine. The technical field of this invention pertains to amino acid production via microbial fermentation. The patent outlines the process of over-expressing genes frd1 and frd2, which encode hypothetical NADPH-dependent FMN reductases in the strain SDNN403. The target proteins, Frd181 and Frd188, are purified and identified for their functions, demonstrating their role as NAD(P)H-dependent flavin reductases that produce HO. The method includes obtaining gene deletion fragments through overlap extension PCR and creating knockout plasmids to transform the SDNN403 strain. The results from flask shaking fermentation indicate a significant increase in L-arginine yield after knocking out the frd1 and frd2 genes.
Career Highlights
Zaiwei Man is affiliated with Jiangnan University, where he conducts his research and development activities. His work has led to advancements in the production of essential amino acids, contributing to the scientific community's understanding of microbial fermentation processes.
Collaborations
Zaiwei Man collaborates with esteemed colleagues, including Zhiming Rao and Xian Zhang. Their combined expertise enhances the research efforts at Jiangnan University, fostering innovation in the field of amino acid production.
Conclusion
Zaiwei Man's contributions to the field of amino acid production through his innovative patent demonstrate his commitment to advancing scientific knowledge and practical applications. His work not only enhances the yield of L-arginine but also showcases the potential of microbial fermentation techniques in biotechnology.