Yutaka Itsuji

Title: Yutaka Itsuji: Innovator in Rocuronium Preparations

Introduction

Yutaka Itsuji is a notable inventor based in Osaka, Japan. He has made significant contributions to the field of pharmaceuticals, particularly in the development of rocuronium preparations. With a total of 3 patents to his name, Itsuji's work focuses on improving the stability and reducing the pain associated with rocuronium use.

Latest Patents

One of Itsuji's latest patents is a rocuronium preparation with improved stability. This invention provides a formulation that contains rocuronium and a buffer solution, adjusted to a pH of 3.5 or less. The buffer solutions can include citric acid-sodium hydroxide, tartaric acid-sodium hydroxide, and others. This preparation demonstrates excellent stability, with a generation rate of rocuronium-related substance C of 5% or less after six months of storage at 40°C.

Another significant patent by Itsuji is a rocuronium preparation designed to cause less pain. This formulation also contains rocuronium and a buffer solution, with a titratable acidity of 100 mEq or less. The buffer solutions may include acetate, citrate, formate, and others. This innovative preparation aims to reduce vascular pain that may be induced during its use.

Career Highlights

Yutaka Itsuji is currently associated with Maruishi Pharmaceutical Co., Ltd., where he continues to advance his research and development efforts. His work has been instrumental in enhancing the safety and efficacy of rocuronium preparations, contributing to better patient outcomes in medical settings.

Collaborations

Some of Itsuji's notable coworkers include Hironori Nagahara and Keisuke Jinbo. Their collaborative efforts have further strengthened the research and development initiatives at Maruishi Pharmaceutical Co., Ltd.

Conclusion

Yutaka Itsuji's innovative contributions to the field of pharmaceuticals, particularly in rocuronium preparations, highlight his commitment to improving medical treatments. His patents reflect a dedication to enhancing drug stability and patient comfort, making a significant impact in the industry.