The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 22, 2020
Filed:
Jun. 26, 2014
Applicant:
Maruishi Pharmaceutical Co., Ltd., Osaka, JP;
Inventors:
Assignee:
MARUISHI PHARMACEUTICAL CO., LTD., Osaka, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/58 (2006.01); A61K 9/08 (2006.01); A61K 47/12 (2006.01); A61K 31/5355 (2006.01); A61K 47/18 (2017.01); A61K 9/00 (2006.01); A61K 47/02 (2006.01);
U.S. Cl.
CPC ...
A61K 31/58 (2013.01); A61K 9/0019 (2013.01); A61K 9/08 (2013.01); A61K 31/5355 (2013.01); A61K 47/02 (2013.01); A61K 47/12 (2013.01); A61K 47/18 (2013.01);
Abstract
The present invention provides a rocuronium preparation with an excellent stability. The rocuronium preparation contains rocuronium and a buffer solution and having an adjusted pH of 3.5 or less (for example, 2.5 to 3.5). The buffer solution may be a citric acid-sodium hydroxide buffer solution, a tartaric acid-sodium hydroxide buffer solution, a potassium hydrogen phthalate-hydrochloric acid buffer solution, a glycine-hydrochloric acid buffer solution, or the like. Such a rocuronium preparation has, for example, after 6-month storage at 40° C., a generation rate of rocuronium-related substance C of 5% or less.