Yunke Song

Title: Innovations of Yunke Song in miRNA Analysis

Introduction

Yunke Song is an accomplished inventor based in Baltimore, MD (US). He has made significant contributions to the field of molecular biology, particularly in the area of miRNA analysis. His innovative approaches have the potential to enhance the accuracy and efficiency of miRNA profiling.

Latest Patents

Yunke Song holds a patent for a groundbreaking invention titled "MiRNA analysis methods." This invention provides a PCR-free, multiplexed ligation assay for miRNA expression analysis. It produces highly quantitative, 10-100 plex miRNA profiling in a single reaction. The methods utilize a 2-step ligation assay to generate an array of miRNA-specific ligation products that can be decoded and quantified by size discrimination methods such as gel electrophoresis or single molecule separation. One embodiment of this invention is a low-cost assay that can be performed using standard tools available in nearly all molecular biology laboratories. This assay requires nothing more than a gel apparatus and reader for detection. Other embodiments include the use of magnetic beads and other size exclusion apparatus, which provide increasingly higher sensitivity, lower sample consumption, and reduced processing steps.

Career Highlights

Yunke Song is affiliated with The Johns Hopkins University, where he continues to advance research in molecular biology. His work has garnered attention for its practical applications and innovative methodologies.

Collaborations

Yunke has collaborated with notable colleagues, including Tza-Huei J Wang and Kelvin J Liu, contributing to the advancement of research in their respective fields.

Conclusion

Yunke Song's contributions to miRNA analysis exemplify the impact of innovative thinking in scientific research. His patented methods offer promising solutions for enhanced miRNA profiling, showcasing the importance of invention in advancing molecular biology.