Location History:
- Winston-Salem, NC (US) (2008 - 2010)
- Clemmons, NC (US) (2012)
Company Filing History:
Years Active: 2008-2012
Title: The Innovations of Inventor Yun-De Xiao
Introduction
Yun-De Xiao is a notable inventor based in Clemmons, NC (US), recognized for his significant contributions to pharmaceutical science. With a total of five patents to his name, he specializes in the development of compounds that address various central nervous system (CNS) disorders. His work focuses on the creation of selective amides and derivatives that interact with neuronal nicotinic receptors, aiming to enhance therapeutic outcomes while minimizing side effects.
Latest Patents
Yun-De Xiao's latest patents showcase his innovative research in the field. One of his remarkable inventions is related to sub-type selective amides of diazabicycloalkanes. This patent discloses novel amide compounds prepared from specific heteroaryl carboxylic acids and diazabicycloalkanes. These compounds exhibit selectivity and bind with high affinity to neuronal nicotinic receptors of the α4β2 subtype in the CNS. Their use can potentially treat and prevent a range of CNS disorders by altering the number of nicotinic cholinergic receptors, exhibiting neuroprotective effects, and avoiding significant adverse side effects.
Another notable patent involves sub-type selective azabicycloalkane derivatives. This invention details amide, ketone, and ester compounds derived from certain azabicycloalkane carboxylic acids. These compounds also demonstrate selectivity for the α4β2 nicotinic receptors, promising to address disorders characterized by dysfunctional neurotransmitter release, such as dopamine release. Again, these compounds are designed to have minimal adverse side effects, making them viable candidates for therapeutic applications.
Career Highlights
Yun-De Xiao currently works at Targacept, Inc., a company recognized for its commitment to developing innovative treatments for CNS disorders. His work has enabled advancements in the understanding and application of nicotinic receptors, ultimately contributing to improved health outcomes for patients with neurological conditions.
Collaborations
Throughout his career, Yun-De Xiao has collaborated with esteemed colleagues, including Philip S Hammond and Anatoly A Mazurov. These partnerships have fostered a productive research environment, enhancing the depth and breadth of innovations emerging from their collective expertise.
Conclusion
Yun-De Xiao stands out as a prolific inventor in the pharmaceutical field. His pioneering patents promise to advance treatment options for various CNS disorders through the development of compounds that bind selectively to nicotinic receptors. As he continues to innovate at Targacept, Inc., his work is likely to make a lasting impact on therapeutic practices and patient care in neurology.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.