Yumin He

Title: Innovations by Inventor Yumin He from Changsha, China

Introduction

Yumin He, an accomplished inventor based in Changsha, China, has made significant contributions to the field of molecular detection, specifically focusing on peptide aptamers and their applications. With a total of two patents to his name, his innovations promise advances in biochemical detection methodologies.

Latest Patents

Yumin He’s latest patents include a novel peptide aptamer developed for the specific recognition of arginine and its specialized applications. The peptide aptamer, documented in his patent, is characterized by a sequence indicated as SEQ ID No. 1. This aptamer is modified to enhance stability and includes groups that serve various functions, such as fluorescent or electrochemical detection signals, as well as affinity ligands. His research predicts through computer-aided molecular docking that this peptide aptamer can specifically bind to L-arginine. Verification using an isothermal titration calorimeter confirms the aptamer's effectiveness, showcasing its advantages in stability, binding ability, specificity, and cost efficiency.

Another significant contribution by Yumin He is the method and sensor for detecting L-arginine, which involves synthesizing ferrocene-functionalized hexadecapeptide dithiocyclopentane (FC-P16 Peptide) and developing a polypeptide composite membrane-modified electrode (FC-P16 Peptide/AuE). This innovative electrode exhibits impressive electrochemical response properties when detecting L-Arg, with a notable linear relationship to L-Arg concentrations in a controlled phosphate-buffered saline environment. The modified electrode displays exceptional reproducibility, repeatability, and selectivity, suggesting its potential utility in life sciences and nutritional health applications.

Career Highlights

Yumin He has contributed to the academic and scientific communities through his work associated with esteemed institutions such as Changsha University of Science and Technology and the Chinese Academy of Sciences. His research has not only expanded the knowledge base within his field but has also provided practical solutions to pressing scientific challenges.

Collaborations

Throughout his career, Yumin He has collaborated with notable colleagues, including Zhong Cao and Zhongliang Xiao. These partnerships have facilitated the exchange of ideas and have been instrumental in driving forward innovative research in molecular recognition and detection.

Conclusion

Yumin He’s innovations in peptide aptamer technology and detection methodologies underscore his role as a leading inventor in the field. With two patents to his credit, his work promises to have impactful applications in various scientific domains. As research continues to evolve, his contributions will likely remain influential in advancing understanding and technology related to biochemical detection.