The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2023

Filed:

Dec. 31, 2019
Applicant:

Changsha University of Science and Technology, Changsha, CN;

Inventors:

Zhong Cao, Changsha, CN;

Ningtao Zhou, Changsha, CN;

Li Zhou, Changsha, CN;

Qin Zhu, Changsha, CN;

Jinglin He, Changsha, CN;

Zhongliang Xiao, Changsha, CN;

Yumin He, Changsha, CN;

Zemeng Feng, Changsha, CN;

Yulong Yin, Changsha, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); C07K 1/107 (2006.01); G01N 27/48 (2006.01);
U.S. Cl.
CPC ...
G01N 27/3277 (2013.01); C07K 1/1077 (2013.01); G01N 27/48 (2013.01);
Abstract

A method and a sensor for detecting L-arginine are provided. The method includes synthesizing ferrocene-functionalized hexadecapeptide dithiocyclopentane (FC-P16 Peptide), preparing a polypeptide composite membrane-modified electrode (FC-P16 Peptide/AuE), detecting L-Arg and other steps. The results show that the polypeptide composite membrane-modified electrode (FC-P16 Peptide/AuE) exhibits excellent electrochemical response properties to L-Arg. In 10 mmol/L phosphate-buffered saline (PBS, pH=7.4), the DPV response peak current of the polypeptide composite membrane-modified electrode has an excellent linear relationship with the L-Arg concentration of 1.0×10mol/L to 1.0×10mol/L, with a detection limit of 1.0×10mol/L. With prominent reproducibility, repeatability and selectivity, the modified electrode has potential application in life science and nutritional health.


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