Tokyo, Japan

Yuko Kusuzaki


Average Co-Inventor Count = 8.0

ph-index = 1

Forward Citations = 1(Granted Patents)


Company Filing History:


Years Active: 2024-2025

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2 patents (USPTO):

Title: Yuko Kusuzaki: Innovator in Cancer Treatment

Introduction

Yuko Kusuzaki, an accomplished inventor based in Tokyo, Japan, has made significant contributions to the field of cancer research through her innovative work on bispecific antibodies. With a focus on developing therapeutic solutions for peritoneal disseminated cancer, her inventions aim to enhance treatment options for patients.

Latest Patents

Yuko Kusuzaki holds a patent for an "Anti-TSPAN8/anti-CD3 bispecific antibody and anti-TSPAN8 antibody." The objective of this invention is to provide antibodies that can be utilized in the treatment or prevention of cancer in humans. By immunizing a human monoclonal antibody producing mouse with cancer cells isolated from patients, she successfully developed two specific antibodies, 16B11 and 16B12. These antibodies selectively bind to peritoneal disseminated cancer cells, targeting a crucial region of the TSPAN8 protein. The bispecific antibody 16B11 shows promising cytotoxic activity against TSPAN8-expressing cancer cells both in vitro and in vivo, demonstrating potential for extending the lives of affected rodents.

Career Highlights

Throughout her career, Yuko Kusuzaki has worked with notable organizations such as Astellas Pharma GmbH and the National Cancer Center. Her contributions to cancer therapy research are underscored by her patent work, which not only showcases her innovative spirit but also reflects her commitment to improving patient outcomes.

Collaborations

Yuko has collaborated with esteemed colleagues, including Yoshiyuki Tenda and Masatoshi Yuri. These partnerships have fostered an environment of shared knowledge and expertise aimed at advancing cancer research and development. Their collaborative efforts have been pivotal in driving forward the innovations behind the bispecific antibody technology.

Conclusion

Yuko Kusuzaki stands out as a pioneering inventor who is committed to enhancing cancer treatment methodologies. Through her patent for the anti-TSPAN8/anti-CD3 bispecific antibody, she exemplifies how scientific innovation can lead to breakthroughs in the fight against cancer. Her dedication to research and collaboration with other professionals reflects a strong commitment to improving health outcomes for patients worldwide.

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