Company Filing History:
Years Active: 2003
Title: Innovations by Yu-Huei Lin in Antibody Repertoire Assembly
Introduction
Yu-Huei Lin is an accomplished inventor based in Sunnyvale, CA. He has made significant contributions to the field of biotechnology, particularly in the assembly and screening of complex human antibody repertoires. His innovative work has the potential to advance therapeutic applications and improve the efficiency of antibody development.
Latest Patents
Yu-Huei Lin holds a patent for "Assembly and screening of highly complex and fully human antibody repertoire in yeast." This patent describes compositions, methods, and kits for generating and screening a library of diverse protein complexes that can bind to other proteins or oligonucleotide sequences. The invention includes a library of expression vectors that express protein complexes, which self-assemble to form structures like double-chain antibody fragments and fully assembled antibodies. The library can be efficiently generated in yeast cells through homologous recombination, allowing for high-throughput screening of protein complexes with high binding affinity.
Career Highlights
Yu-Huei Lin is currently associated with Genetastix Corporation, where he continues to innovate in the field of antibody research. His work has garnered attention for its potential applications in therapeutic development and protein engineering.
Collaborations
Yu-Huei Lin collaborates with notable colleagues, including Li Zhu and Shaobing Benjamin Hua, who contribute to the research and development efforts at Genetastix Corporation.
Conclusion
Yu-Huei Lin's innovative work in antibody repertoire assembly represents a significant advancement in biotechnology. His contributions are paving the way for new therapeutic solutions and enhancing the efficiency of antibody development processes.