Company Filing History:
Years Active: 1989-1993
Title: Yu-An Chang: Innovator in Biologically Active Organic Ligands
Introduction
Yu-An Chang is a notable inventor based in Costa Mesa, CA. He has made significant contributions to the field of polymeric carriers and biologically active organic ligands. With a total of 2 patents, his work has implications in both medical and research applications.
Latest Patents
Yu-An Chang's latest patents include innovative methods for activating hydroxyl groups of polymeric carriers. The first patent describes a method of binding biologically active organic ligands to hydroxyl groups of polymeric carriers. This method involves bringing 4-fluorobenzenesulfonyl chloride into reactive contact with the hydroxyl groups, forming sulfonate groups in place of the hydroxyl groups. The ligand is then introduced to replace the sulfonate groups, allowing the polymeric carrier to isolate biologically active materials from heterogeneous solutions. His second patent focuses on the preparation of 8-Chloroadenosine 3', 5'-cyclic monophosphate, a compound used to treat malignant tumors in warm-blooded animals. This patent discloses two novel single-step syntheses of 8-chloroadenosine 3',5'-cyclic phosphate and related compounds.
Career Highlights
Throughout his career, Yu-An Chang has worked with prominent organizations such as the Nucleic Acid Research Institute and Baxter International Inc. His experience in these institutions has allowed him to develop and refine his innovative techniques in the field of biochemistry.
Collaborations
Yu-An Chang has collaborated with notable colleagues, including Roland K. Robins and Ganapathi R. Revankar. These partnerships have contributed to the advancement of his research and the successful development of his patents.
Conclusion
Yu-An Chang's contributions to the field of biologically active organic ligands and polymeric carriers highlight his innovative spirit and dedication to scientific advancement. His patents reflect a commitment to improving medical treatments and research methodologies.
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