The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 20, 1993
Filed:
Aug. 13, 1990
Applicant:
Inventor:
Yu-An Chang, Costa Mesa, CA (US);
Assignee:
Baxter International Inc., Deerfield, IL (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C12N / ; C12N / ; G01N / ;
U.S. Cl.
CPC ...
530413 ; 435178 ; 435179 ; 435180 ; 435803 ; 436529 ; 436530 ; 436531 ; 436824 ; 530813 ; 530814 ; 530815 ;
Abstract
The invention relates to a method of binding biologically active organic ligands to hydroxyl groups of polymeric carriers. The method involves bringing 4-fluorobenzenesulfonyl Chloride into reactive contact with the hydroxyl groups of polymeric carriers in such a manner to form sulfonate groups in place of the hydroxyl groups. The ligand is then brought into reactive contact with the hydroxyl groups of polymeric carriers to replace the sulfonate groups reacted with the organic ligand. The polymeric carrier containing the bound ligand can be used to isolate a biologically active material from a heterogeneous solution.