Company Filing History:
1 out of 266 
1 out of 1 
1 out of 3 Years Active: 1989-2004
Title: Innovations by Yoshitsugi Hokama
Introduction
Yoshitsugi Hokama is an accomplished inventor based in Honolulu, HI (US). He has made significant contributions to the field of marine toxin detection, holding a total of 3 patents. His work focuses on developing rapid testing methods for ciguatoxin and related marine toxins, which are crucial for ensuring food safety.
Latest Patents
Hokama's latest patents include a membrane immunobead assay for the detection of ciguatoxin and related polyether marine toxins. This innovative immunological test kit is designed for the rapid detection of ciguatoxin in fish tissues, whether in the field, at home, or in a laboratory setting. The test procedure involves a synthetic membrane laminated onto a solid plastic stick, which is immersed in alcohol with a piece of fish tissue. After drying, the membrane is placed in a suspension of mixed colored beads coated with anti-ciguatoxin. The intensity of the color is then compared to a standard range, providing a proportional measure of toxin concentration.
Another notable patent is the immuno-latex chromatographic procedure for the detection of ciguatoxin. This antibody test allows for the rapid detection of ciguatoxin and other related low molecular weight polyether marine lipid toxins in fish tissue. The test utilizes the reaction between antibody-coated mixed latex beads and lipids in an extract of fish tissue. Results can be determined within about thirty minutes through ascending chromatography, which separates the mixed beads. A kit for performing this testing procedure in the field is also included, featuring a nylon membrane covering and a supply of solvent.
Career Highlights
Hokama has worked with reputable institutions such as the University of Hawai'i and the Asian Pacific Research Foundation. His contributions to marine science and toxin detection have been invaluable in promoting food safety and public health.
Collaborations
Some of his notable coworkers include Joanne S. M. Ebesu and Warren E. Takenaka. Their collaborative efforts have further advanced the research and development of effective testing methods for marine toxins.
Conclusion
Yoshitsugi Hokama's innovative work in the detection of marine toxins has made a significant impact on food safety. His patents reflect a commitment to developing practical solutions for real-world challenges.