Location History:
- Saitama, JP (2012)
- Tokyo, JP (2005 - 2014)
Company Filing History:
5 out of 373 
3 out of 1,309 
1 out of 1,710 
Years Active: 2005-2014
Title: Innovations of Yoshio Umezawa
Introduction
Yoshio Umezawa is a prominent inventor based in Tokyo, Japan. He has made significant contributions to the field of science and technology, particularly in the area of nitric oxide detection and protease activation. With a total of 10 patents to his name, Umezawa's work has had a substantial impact on research and development.
Latest Patents
Umezawa's latest patents include a probe for the detection and quantification of nitric oxide. This innovative probe comprises two subunits of soluble guanylate cyclase and cGMP-visualization probes, which are connected to generate a signal upon recognizing guanosine 3',5'-cyclic monophosphate. Another notable invention is an activated protease indicator, which provides novel approaches for detecting activated protease in real-time with high sensitivity in a noninvasive manner. This method utilizes an indicator in a circular form, comprising the C-half fragment of luciferase and the N-half fragment of luciferase linked through a substrate peptide for a protease. Upon digestion of the substrate peptide by the protease, the fragments reconstruct active luciferase, allowing for the detection of activated protease through luminescence signal assays.
Career Highlights
Throughout his career, Umezawa has worked with esteemed organizations such as the Japan Science and Technology Corporation and the Japan Science and Technology Agency. His contributions to these institutions have furthered advancements in scientific research and innovation.
Collaborations
Umezawa has collaborated with notable colleagues, including Moritoshi Sato and Takeaki Ozawa. These partnerships have enriched his research endeavors and expanded the scope of his inventions.
Conclusion
Yoshio Umezawa's innovative work in the field of nitric oxide detection and protease activation showcases his expertise and dedication to scientific advancement. His patents and collaborations reflect a commitment to pushing the boundaries of technology and research.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.