Company Filing History:
Years Active: 1995-1998
Title: **Yoshio Kobayashi: A Pioneer in Lymphotoxin Research**
Introduction
Yoshio Kobayashi, an innovative inventor based in Frederick, MD, has made significant contributions to the field of biotechnology. With a remarkable portfolio comprising two patents, Kobayashi is renowned for his work in the production and application of lymphotoxins.
Latest Patents
Kobayashi's recent patents focus on advanced methodologies for producing lymphotoxins from human T-cell hybridomas. The first patent details a process wherein these hybridomas are incubated in a specific medium, followed by fractionation through sucrose density-gradient centrifugation to isolate messenger RNA in the 12.6S to 14.6S ranges. This process allows for the preparation of a gene that encodes a polypeptide with lymphotoxin activity. His second patent describes a similar methodology for the production of lymphotoxin (TNFB) in the A-C5-8 cell line, utilizing the same incubation and fractionation techniques to yield new lymphotoxins through genetic engineering technologies.
Career Highlights
Kobayashi is affiliated with Denki Kagaku Kogyo Kabushiki Kaisha, a company recognized for its achievements in chemical engineering and biotechnology. Throughout his career, he has focused on harnessing the potential of lymphotoxins, which play a crucial role in immune response and may have therapeutic applications.
Collaborations
Yoshio Kobayashi has collaborated with notable colleagues such as Toshiaki Osawa and Masuo Obinata. These partnerships have fostered a dynamic research environment, contributing to advancements in their shared interests of biotechnology and immunology.
Conclusion
Yoshio Kobayashi's work underscores the importance of innovation within the biotechnology sector. His patents not only represent significant scientific advancements but also pave the way for future research and applications in lymphotoxin production. As he continues to contribute to the field, Kobayashi's legacy as a pioneering inventor will undoubtedly inspire future generations of researchers and inventors.