Company Filing History:
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Years Active: 2021-2023
Title: Yoshihisa Hagihara: Innovator in Nucleic Acid Amplification Technology
Introduction
Yoshihisa Hagihara is a prominent inventor based in Ikeda, Japan. He has made significant contributions to the field of nucleic acid amplification technology, holding 2 patents that showcase his innovative approach to enhancing diagnostic methods.
Latest Patents
Hagihara's latest patents include a nucleic acid amplification device, a nucleic acid amplification method, and a chip for nucleic acid amplification. The present invention provides a reciprocal-flow-type nucleic acid amplification device that comprises heaters capable of forming a denaturation temperature zone and an extension/annealing temperature zone. It features a fluorescence detector that can detect the movement of a sample solution between the two temperature zones. Additionally, the device includes a pair of liquid delivery mechanisms that allow the sample solution to move between the two temperature zones and are configured to be open to atmospheric pressure when liquid delivery stops. A substrate is provided on which the chip for nucleic acid amplification can be placed, along with a control mechanism that manages the driving of each liquid delivery mechanism by receiving an electrical signal from the fluorescence detector. This device is capable of performing real-time PCR by measuring fluorescence intensity for each thermal cycle.
Career Highlights
Throughout his career, Yoshihisa Hagihara has worked with esteemed organizations such as the National Institute of Advanced Industrial Science and Technology and Kyorin Pharmaceutical Co., Ltd. His work in these institutions has allowed him to develop and refine his innovative technologies in nucleic acid amplification.
Collaborations
Hagihara has collaborated with notable colleagues, including Hidenori Nagai and Shunsuke Furutani. These partnerships have contributed to the advancement of his research and the successful development of his patented technologies.
Conclusion
Yoshihisa Hagihara's contributions to nucleic acid amplification technology highlight his role as an influential inventor in the field. His innovative devices and methods continue to impact the landscape of molecular diagnostics.