Ibaraki, Japan

Yoshie Takahashi

USPTO Granted Patents = 2 


 

Average Co-Inventor Count = 5.5

ph-index = 1

Forward Citations = 13(Granted Patents)


Location History:

  • Tsukuba, JP (2013)
  • Ibaraki, JP (2016)

Company Filing History:


Years Active: 2013-2016

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2 patents (USPTO):

Title: Innovations by Yoshie Takahashi: Advancements in Sugar Chain Production

Introduction

Yoshie Takahashi, an esteemed inventor based in Ibaraki, Japan, has made remarkable contributions to the field of biochemistry. With 2 patents to her name, she has significantly advanced the production of complex sugar chains and proteins, addressing key challenges in the pharmaceutical industry.

Latest Patents

Takahashi's latest patents focus on two innovative methods. The first patent, titled "Method for producing sialic-acid-containing sugar chain," addresses the critical need for industrial production of sugar chains featuring α2,3- or α2,6-linked sialic acid at their non-reducing ends. This invention outlines a process utilizing sialyltransferase to efficiently produce complex sugar chains, including those difficult to synthesize chemically or enzymatically. The one-pot synthesis approach allows for high yields of tetraantennary N-type sugar chains, which have historically posed significant production challenges.

The second patent, "Method for high-level secretory production of protein," outlines a strategy for producing proteins with complex structures, such as antibodies, in host cells like yeast. This method utilizes transformed host cells containing chaperone protein genes to enhance the secretory production of foreign proteins while suppressing the inherent O sugar chains of the yeast.

Career Highlights

Throughout her career, Yoshie Takahashi has worked with prominent organizations such as the National Institute of Advanced Industrial Science and Technology and Kyowa Hakko Kirin Co., Limited. Her role in these institutions highlights her commitment to pushing the boundaries of scientific discovery and advancement in the biotechnology sector.

Collaborations

In her journey, Takahashi has collaborated with esteemed colleagues like Yasunori Chiba and Yoshifumi Jigami. These partnerships have enriched her research endeavors, fostering an environment of innovation and interdisciplinary cooperation.

Conclusion

Yoshie Takahashi's impactful work in the field of biochemistry showcases her ingenuity and dedication to solving complex challenges. Her patents on sugar chain production and protein synthesis offer valuable advancements that could reshape therapeutic approaches in the medical field. As she continues to push the envelope of innovation, the scientific community looks forward to her future contributions.

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