The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 02, 2013
Filed:
Oct. 29, 2008
Yasunori Chiba, Tsukuba, JP;
Yoshifumi Jigami, Tsukuba, JP;
Yoshie Takahashi, Tsukuba, JP;
Kosuke Kuroda, Takasaki, JP;
Kazuo Kobayashi, Takasaki, JP;
Kimihisa Ichikawa, Edogawa-ku, JP;
Koichi Nonaka, Iwaki, JP;
Takeshi Suzuki, Iwaki, JP;
Minako Ono, Iwaki, JP;
Yasunori Chiba, Tsukuba, JP;
Yoshifumi Jigami, Tsukuba, JP;
Yoshie Takahashi, Tsukuba, JP;
Kosuke Kuroda, Takasaki, JP;
Kazuo Kobayashi, Takasaki, JP;
Kimihisa Ichikawa, Edogawa-ku, JP;
Koichi Nonaka, Iwaki, JP;
Takeshi Suzuki, Iwaki, JP;
Minako Ono, Iwaki, JP;
National Institute of Advanced Industrial Science and Technology, Tokyo, JP;
Kyowa Hakko Kirin Co., Ltd, Tokyo, JP;
Daiichi Sankyo Company, Limited, Tokyo, JP;
Abstract
This invention provides a means for high-level secretory production of a protein, and, in particular, a protein having a complicated structure such as an antibody, in a host cell such as a yeast cell. This invention provides a method for high-level secretory production of a foreign protein with the use of a transformed host cell having one or more types of chaperone protein genes and via suppression of O sugar chain inherent to a host cell such as a yeast cell.