Location History:
- Hubei, CN (2015)
- Wuhan, CN (2017 - 2023)
Company Filing History:
Years Active: 2015-2025
Title: **The Innovative Contributions of Yongxiang Yan from Wuhan, China**
Introduction
Yongxiang Yan is a prominent inventor based in Wuhan, China, known for his significant contributions to biotechnology and therapeutic antibody development. With a total of three patents to his name, Yongxiang has been instrumental in advancing innovations that hold great potential for medical applications.
Latest Patents
Yongxiang Yan's recent patents showcase his expertise in the field of antibodies. One of his notable inventions is the "CD3 antigen binding fragment and application thereof." This patent provides a humanized and multifunctional CD3 antibody. It includes a heavy chain variable region featuring amino acid sequences defined in SEQ ID NOs: 1-3 or their variants, along with a light chain variable region with sequences outlined in SEQ ID NOs: 26-28 or their variants. This multifunctional antibody is designed with specificity for tumor cells or microorganisms and includes a fusion peptide that combines a single-chain variable fragment with an Fc fragment, enhancing its specificity for immune cells. These innovations boast improved biological activity, thermal stability, and acid resistance.
Another critical invention is his patent for bispecific antibodies. This invention consists of a single-chain unit with specificity for immune cells and a monovalent unit for tumor cells or microorganisms. The structural components include a single-chain variable fragment (scFv) fused to an Fc fragment, alongside a traditional light and heavy chain pair. This invention also outlines methods for preparing these bispecific antibodies and discusses their pharmaceutical and diagnostic applications.
Career Highlights
Yongxiang Yan currently works at Wuhan Yzy Biopharma Co., Ltd., where he focuses on developing cutting-edge therapeutic solutions. His commitment to innovation and research has established him as a key figure in his field, and his patents reflect a deep understanding of immunology and biotechnology.
Collaborations
Throughout his career, Yongxiang has collaborated with notable colleagues like Pengfei Zhou and Jing Zhang. These collaborations have allowed him to combine expertise and drive forward significant contributions to the field of biopharmaceuticals.
Conclusion
Yongxiang Yan is a leading inventor whose work at Wuhan Yzy Biopharma Co., Ltd. demonstrates the power of innovation in biotechnology. His patented inventions in antibody development are paving the way for novel therapeutic strategies that could potentially transform patient care. As he continues to pioneer advancements, Yongxiang’s impact on the field will surely be profound.