This inventor holds 2 USPTO granted patents and 3 published patent applications and 1 EPO patent. Top assignee: Princeton University. Active years: 2020-2021.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2020-2021
Title: Innovations of Yongdae Shin in Protein Clustering
Introduction
Yongdae Shin is a prominent inventor based in Lawrenceville, NJ (US). He has made significant contributions to the field of protein engineering, particularly in the development of optogenetic tools. With a total of 2 patents, his work is paving the way for advancements in protein purification and cellular biology.
Latest Patents
One of Yongdae Shin's latest patents is an optogenetic tool for rapid and reversible clustering of proteins. This innovative protein construct includes a gene encoding a light-sensitive protein fused to either a low complexity sequence, an intrinsically disordered protein region (IDR), or a repeating sequence of a linker along with another gene encoding a light-sensitive protein. The construct may also include cleavage tags, enhancing its functionality. This tool can be utilized for various applications, including a method for protein purification that involves introducing the protein construct into living cells and inducing cluster formation through light irradiation. Additionally, the method allows for the cleavage of a target protein from an IDR and the separation of clusters via centrifuge. A kit for practicing in vivo aggregation or liquid-liquid phase separation is also included, featuring the protein construct and a light source that activates the light-sensitive protein.
Career Highlights
Yongdae Shin is affiliated with Princeton University, where he continues to push the boundaries of research in protein engineering. His work has garnered attention for its potential applications in biotechnology and medicine.
Collaborations
Some of his notable coworkers include Jared Toettcher and Cliff Brangwynne, who contribute to the collaborative research environment at Princeton University.
Conclusion
Yongdae Shin's innovative work in the field of protein clustering represents a significant advancement in biotechnology. His patents and research are likely to have a lasting impact on the scientific community and beyond.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile