Company Filing History:
Years Active: 2019-2023
Title: Innovations in RNA Technologies by Inventor Yinong Yang
Introduction
Yinong Yang is an accomplished inventor based in State College, PA, known for his impactful contributions to the field of RNA technologies. With two patents to his name, Yang's innovative methods focus on advancing genome editing and genetic manipulation techniques.
Latest Patents
Yang's latest patents include "Methods and compositions for multiplex RNA guided genome editing and other RNA technologies." This invention encompasses materials and methodologies designed to produce numerous small RNA molecules from a single polynucleotide construct, or synthetic gene. The synthetic gene/polynucleotide construct is structured to encode polycistronic RNA components that are separated by tRNAs. It also incorporates essential regulatory components, such as a promoter or terminator, effectively creating an expression cassette. Once transcribed within a cell, the transcript undergoes processing by the cell's endogenous tRNA processing system, yielding multiple RNA molecules. This innovative approach can be employed in various RNA-based gene manipulation techniques, including RNA-mediated genome editing, artificial microRNA-mediated gene silencing, small RNA-mediated genetic manipulation, double-stranded RNA-mediated gene silencing, and antisense mechanisms.
Career Highlights
Throughout his career, Yinong Yang has established himself as a notable figure in biotechnology and genetic engineering. His work at the Penn State Research Foundation underscores his commitment to advancing the frontiers of science and technology. Yang's contributions to the field have significantly impacted research and applications in genome editing.
Collaborations
Yang collaborates with Kabin Xie, a colleague who shares his passion for innovative research. Their partnership fosters an environment of creativity and collaboration, leading to more groundbreaking advancements in RNA technology.
Conclusion
Yinong Yang's innovative work in RNA technologies positions him as a leading inventor in the biotechnology industry. With his patents focusing on multiplex RNA-guided genome editing, he continues to shape the future of genetic research and applications. His contributions at the Penn State Research Foundation and collaborations with colleagues enhance the potential for groundbreaking discoveries in the field.