Company Filing History:
Years Active: 2000-2002
Title: Yinong Ma: Innovator in Polymer Delivery Systems and Phosphorous Acid Production
Introduction
Yinong Ma is a notable inventor based in Westfield, MA (US). He holds a total of 3 patents that showcase his contributions to the fields of polymer delivery systems and chemical processes.
Latest Patents
One of his latest inventions is a ph-selective delivery system using crosslinked polymeric resins as vehicles. This invention provides a method of preparing a polymeric delivery system for active ingredients that have enhanced site-specific release performance characteristics. The delivery system is formed by attaching the active ingredient to a linker through an acid-sensitive covalent bond, followed by forming a covalent bond between the linker and a portion of the subunits of a crosslinked polystyrene polymer. Additionally, the invention includes a delivery system comprising an active ingredient covalently bonded through an acid-sensitive covalent bond to a linker, which is in turn covalently bonded to a portion of subunits of a crosslinked polystyrene polymer. Furthermore, it provides a method for the treatment or prevention of gastric ulcers using a delivery system capable of delivering prostaglandin or prostacyclin drugs, especially misoprostol.
Another significant patent is a process for producing phosphorous acid. This process involves the selective hydrolysis of phosphite esters. A hydrolysis feed mixture comprising phosphite esters and phosphate esters is contacted with liquid water or steam to selectively hydrolyze the phosphite esters to phosphorous acid. The feed mixture may be prepared by oxidation of elemental phosphorous in the presence of an alcohol. In the oxidation and/or a subsequent esterification step, P(III) and P(V) oxyacids produced in the oxidation reaction are esterified, preferably quantitatively.
Career Highlights
Yinong Ma has worked with prominent companies such as Monsanto Company and Pharmacia Corporation. His experience in these organizations has contributed to his expertise in the field of chemical engineering and innovation.
Collaborations
Some of his notable coworkers include Samuel J Tremont and Denis Forster. Their collaborations have likely played a role in advancing the projects they worked on together.
Conclusion
Yinong Ma's innovative work in polymer delivery systems and phosphorous acid production highlights his significant contributions to the field of chemistry and engineering. His patents reflect a commitment to