Yifat Oren

Title: Yifat Oren: Innovator in CFTR Gene Modulation

Introduction

Yifat Oren is a notable inventor based in Jerusalem, Israel. He has made significant contributions to the field of genetic research, particularly in the modulation of the CFTR gene, which is crucial for cystic fibrosis treatment. His innovative work has the potential to impact therapeutic approaches for this genetic disorder.

Latest Patents

Yifat Oren holds 1 patent for his invention titled "Restoration of the CFTR function by splicing modulation." This patent provides oligonucleotides capable of binding to and modulating the splicing of the pre-mRNA of the CFTR gene. The invention includes compositions comprising these oligonucleotides and their uses, such as suppressing the inclusion of a cryptic exon between exon 22 and 23 due to the mutation 3849+10Kb C-to-T. This innovative approach can be used in combination with additional cystic fibrosis therapeutics.

Career Highlights

Throughout his career, Yifat Oren has worked with prominent organizations, including Yissum Research Development Company of the Hebrew University of Jerusalem and Splisense Ltd. His experience in these companies has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.

Collaborations

Yifat Oren has collaborated with notable colleagues, including Bat Sheva Kerem and Efrat Ozeri-Galai. These partnerships have enhanced his research and development efforts in the area of genetic modulation.

Conclusion

Yifat Oren's innovative work in CFTR gene modulation exemplifies the impact of research on genetic disorders. His contributions are paving the way for new therapeutic strategies in the treatment of cystic fibrosis.