Yi-Ming Zhang

Title: The Innovative Contributions of Yi-Ming Zhang

Introduction

Yi-Ming Zhang is a notable inventor based in Falls Church, VA (US). He has made significant contributions to the field of virology, particularly in the development of vaccines. With a total of 2 patents, his work focuses on innovative approaches to combat flavivirus-related diseases.

Latest Patents

One of Yi-Ming Zhang's latest patents involves the creation of chimeric and/or growth-restricted flaviviruses. This invention includes a chimeric virus designed for use in vaccine preparation. The genome of this virus comprises nucleic acid sequences encoding at least one structural protein from one flavivirus and nonstructural protein sequences from another. The genome is engineered with mutations that reduce virus virulence, making it particularly effective against flaviviruses such as dengue virus, tick-borne encephalitis virus, and Japanese encephalitis virus. Additionally, the invention encompasses a baculovirus with a recombinant dengue cDNA sequence, which encodes various dengue virus proteins. It also includes a baculovirus with a recombinant Japanese B encephalitis virus cDNA sequence, further contributing to vaccine development.

Career Highlights

Yi-Ming Zhang is affiliated with the National Institutes of Health, a component of the US Department of Health & Human Services. His work at this prestigious institution has allowed him to focus on groundbreaking research in vaccine development and virology.

Collaborations

Some of his notable coworkers include Ching-Juh Lai and Michael Bray. Their collaborative efforts have contributed to advancing research in the field of flavivirus vaccines.

Conclusion

Yi-Ming Zhang's innovative work in developing chimeric flaviviruses for vaccine preparation highlights his significant contributions to public health. His research continues to pave the way for effective treatments against viral diseases.