Yeuk-Chuen Liu

Title: Yeuk-Chuen Liu: Innovator in Chemical Processes

Introduction

Yeuk-Chuen Liu is a notable inventor based in Hsinchu, Taiwan. He has made significant contributions to the field of chemical processes, particularly in the preparation of various compounds. With a total of two patents to his name, Liu's work has implications in the pharmaceutical industry.

Latest Patents

Liu's latest patents include a process for preparing an acylation process using a sulfonic acid, a salt of the sulfonic acid, or a mixture thereof, as a catalyst. This innovative method involves protecting the 4-hydroxyl group on the pyranone ring of the 8'-hydroxy compound to form a beta-protected compound. The acylation of the 8-hydroxy group on the polyhydronaphthyl ring leads to the formation of a protected ester, which is further processed to yield the desired compound. Another significant patent details the process for preparing compound 2 by reacting compound 1 with a tetraalkyl ammonium hydroxide, resulting in a triol carboxylate that is acidified and lactonized to obtain a diol lactone, a key intermediate for antihypercholesterolemia agents.

Career Highlights

Throughout his career, Liu has worked with prominent organizations such as the Industrial Technology Research Institute and Yung Shin Pharmaceutical Industries Co., Ltd. His experience in these institutions has allowed him to refine his expertise in chemical processes and contribute to advancements in the field.

Collaborations

Liu has collaborated with various professionals, including Yuh-Lin Allen Yang, enhancing the scope and impact of his research and innovations.

Conclusion

Yeuk-Chuen Liu's contributions to chemical processes and his innovative patents highlight his role as a significant inventor in the pharmaceutical industry. His work continues to influence advancements in the preparation of important compounds.